Bronze

BioMarin Pharmaceutical

With six products on the market and a fully-integrated multinational organization in place, BioMarin is providing innovative therapeutics to patients with serious unmet medical needs. The company is also currently conducting a clinical trial of an AAV-based potential gene therapy for hemophilia A.

SwanBio Therapeutics

SwanBio Therapeutics aims to bring life-changing treatments to people with devastating, inherited neurological conditions. The company is advancing a pipeline of gene therapies designed to be delivered intrathecally to address targets within both the central and peripheral nervous systems. SwanBio’s lead program is the first clinical-stage AAV-based gene therapy for the treatment of adrenomyeloneuropathy (AMN).
 

SparingVision

SparingVision is a genomic medicines company with a mission to translate pioneering science into vision saving treatments. Leveraging its unparalleled understanding of retinal diseases, SparingVision has built the world’s most compelling portfolio of synergistic cutting-edge gene therapy and genome editing treatments for inherited retinal diseases (IRDs). Both of its most advanced products, SPVN06 and SPVN20 look to go beyond single gene correction therapies to deliver new mutation agnostic treatments for Retinitis Pigmentosa (RP), a group of IRDs which are the leading cause of blindness globally. The Company also has a strategic collaboration with Intellia Therapeutics (NASDAQ:NTLA) to develop novel genome editing-based treatments for ocular diseases utilizing CRISPR-Cas9 technology.

SparingVision is backed by high-quality international investors including 4BIO Capital, AdBio Partners, Bpifrance, Foundation Fighting Blindness (US), Fondation Voir & Entendre, Intellia Therapeutics, UPMC Enterprises, Jeito Capital, Ysios Capital.
 

ViroCell

Powering innovation on its journey from lab to life. 
 
ViroCell Biologics is a UK-based innovation-driven Contract Development and Manufacturing Organization (CDMO) that manufactures viral vectors and gene-modified cells to enable novel cell and gene therapies to enter clinical trials. 
 
 

Diamond

MaxCyte

MaxCyte is a leading provider of cell-engineering platform technologies that are driving the next-generation of cell-based therapies and making a meaningful difference for patients. The Company's technology is employed by leading drug developers worldwide, including all of the top ten global biopharmaceutical companies. MaxCyte has granted 13 strategic platform licenses to leading cell-based therapy developers. Through 2020, MaxCyte has granted licenses for more than 140 cell therapy programs, with over 100 licensed for clinical use. Our Flow Electroporation® technology and next-generation ExPERT® platform enable our partners to accelerate, streamline, and improve the drug development process from the early stages of research to commercialization. MaxCyte was founded in 1998 and is headquartered in Gaithersburg, Maryland, U.S.
 

Sartorius

The Sartorius Group is a leading international partner of the biopharmaceutical industry and the research sector. We are helping biotech scientists and engineers across the entire globe to develop and manufacture medications from the first idea to production. So more people will have access to better medicine.
Sartorius offers the Nutristem® and 4Cell® Nutri-T range of serum-free, xeno-free media for stem cells (MSCs, iPSCs, and ESCs) and T cells, which have become the gold standard in  research and clinical applications, helping to advance stem cell and lymphocyte based therapies.
Sartorius supplies additional related products for stem and T cell culture, including animal component-free freezing media, xeno-free attachment solutions and animal component-free cell dissociation solutions.
 

Thermo Fisher Scientific

As the world leader in serving science, Thermo Fisher Scientific is uniquely positioned to provide the quality materials, services and support need to accelerate the pace of advanced therapy development. We understand the complexity of this rapidly-evolving industry and have made significant investments in cGMP raw material manufacturing and drug product manufacturing capabilities to provide innovative end-to-end solutions- from the acquisition of Brammer Bio to investing to expand our critical raw material manufacturing facilities. Partner with us to access the high-quality materials, services, and support you need from discovery to clinical research and commercial cell and gene manufacturing. Through our Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab services, Patheon, and Gibco brands, we offer an unmatched combination of innovative technologies, manufacturing, and distribution capabilities.

PTC Therapeutics

PTC is a science-driven, global biopharmaceutical company focused on the discovery, development and commercialization of clinically differentiated medicines that provide benefits to patients with rare disorders. PTC’s ability to globally commercialize products is the foundation that drives investment in a robust and diversified pipeline of transformative medicines and our mission to provide access to best-in-class treatments for patients who have an unmet medical need. To learn more about PTC, please visit us at www.ptcbio.com and follow us on Facebook, on Twitter at @PTCBio, and on LinkedIn.
 

Gold

Genethon

Genethon, is a pioneer and a leader in the field of gene therapy for rare genetic diseases. Genethon has multiple ongoing programs at clinical, preclinical and research stage for neuromuscular, blood, immune system, and liver diseases. Several of these programs are pursued by Genethon as sponsor, others have been licensed to leading biotech and pharma players in the gene therapy arena such as Avexis/Novartis (to which Genethon licensed the founding patents for Zolgensma), Audentes, Gensight Biologics, Orchard Therapeutics, Spark.
Genethon has around 200 scientists and experts in its R&D center in Evry (France), covering R&D, bioprocess development, clinical and regulatory.
Genethon is a non-profit organization created in 1990 by the AFM-Telethon (French Muscular Dystrophy Association) which is its main funding source.
 

Human Gene Therapy

Established in 1990, Human Gene Therapy is the leading peer-reviewed journal publishing exceptional, multidisciplinary research embracing all aspects of gene therapy - from basic research to new technologies to clinical development. In 2020 the Journal marked three impressive decades by unveiling a dramatic new redesign and a renewed editorial mission. Human Gene Therapy serves as the Official Journal of ESGCT.

Oxford Biomedica

A leading, fully integrated, cell and gene therapy group focused on developing life-changing treatments for serious diseases, Oxford Biomedica is your partner of choice for viral vector development scale-up, analytics and GMP processing.
Leverage our expertise and state-of-the-art bioprocessing facilities and purpose built laboratories to help to achieve commercialisation of your viral vector-based products.
Using LentiVector®, our sector leading lentiviral vector platform, Oxford Biomedica develops in vivo and ex vivo products both in-house and with partners, including with Novartis, Bristol Myers Squibb, Sio Gene Therapies, Orchard Therapeutics, Santen, Beam Therapeutics, Boehringer Ingelheim, the UK Cystic Fibrosis Gene Therapy Consortium and Imperial Innovations.
Additionally, Oxford Biomedica has a 3-year master supply and development agreement with AstraZeneca for large-scale manufacturing of the adenoviral based COVID-19 vaccine, AZD1222.
Discover how we drive credible science to help you realise incredible results - visit www.oxb.com or email partnering@oxb.com.
 
 

Yposkesi

YPOSKESI, based in Corbeil-Essonnes, near Paris (France), is one of the largest European Contract Development and Manufacturing Organizations dedicated to the development and production of gene and cell therapy treatments. The broad expertise of YPOSKESI covers the production of Lentivirus & AAV viral vectors based on transfection processes, for pre-clinical development and clinical trials in compliance with the standards of Good Manufacturing Practice regulations. YPOSKESI benefits from the 30 years viral vector expertise of its long-standing partner, GENETHON, a major player in gene therapies for rare disease.
 
In addition, YPOSKESI has an experienced and efficient team of nearly 190 experts in Bioproduction, Quality Assurance, Quality Control, Project Management and Process Development, operating in a 5,000m2 (approx. 53,819 sq ft) modern GMP facility. YPOSKESI is also significantly investing in the development of innovative technologies for large-scale cost-effective manufacturing of these highly complex Advanced Therapeutics Medicinal Products. YPOSKESI plans to extend its production capacity by 2022, with an additional building including two suites dedicated to commercial manufacturing activities with a total of 10,000 m² (approx. 107639 sq ft) space.
 
By forging a solid industrial partnership with the South-Korean SK group, its majority equity shareholder, YPOSKESI reinforced its industrial strategy based on the technological expertise of SK pharmteco, the US SK’s affiliate, complementing that of YPOSKESI, and its solid experience in international manufacturing as a contract manufacturing organisation (CMO).
 

Cevec Pharmaceuticals

CEVEC is a leading provider of high-performance cell technology for the manufacturing of advanced bio-therapeutics from R&D to manufacturing scale. The company’s product portfolio comprises platform technologies for gene therapy viral vectors, vaccines and complex recombinant proteins. With the ELEVECTA® Technology, CEVEC offers a unique solution for large-scale production of AAV vectors using helper virus-free producer cell lines with all necessary components stably integrated into the cell. The technology is based on suspension cells and does not require any expensive transfection reagents and cGMP plasmids. CEVEC’s CAP® Technology based on human suspension cells is the ideal production platform for RCA-free Adenoviral vectors, Lentiviral vectors, viral vaccines and exosomes. With the CAP-Go® Technology CEVEC provides a solution to the increasing need for recombinant production of complex and highly glycosylated protein molecules, including laminins, coagulation factors and plasma proteins.
 

GenScript Biotech

GenScript is a world leader in biotechnology reagent services, providing life sciences services and products to over 200,000 scientists in over 100 countries worldwide. Established in 2002 in New Jersey, United States, the company was one of the first to commercialize gene synthesis as well as establish fully integrated capabilities for custom peptide synthesis, complex protein expression and engineering, custom antibody development and engineering, in vitro/in vivo pharmacology, as well as a variety of other research-focused catalogue products.
 
After almost two decades of rapid growth, the company has expanded its business in recent years into the fields of immunotherapy, CDMO and microbiology to further its core mission of making people and nature healthier through biotechnological innovation.
 
With global support from its loyal customers and over 2600 employees located across the globe, GenScript continues to strive towards their vision of being the most reliable biotech company in the world, in service of a better and healthier future.
 

Cytiva

Cytiva is a global life sciences leader dedicated to advancing and accelerating therapeutics. Cytiva is a trusted partner to customers that undertake life-saving activities ranging from biological research to developing innovative vaccines, biologic drugs, and novel cell and gene therapies. Cytiva brings speed, efficiency and capacity to research and manufacturing workflows, enabling the development, manufacture and delivery of transformative medicines to patients.

Tataa Biocenter

TATAA Biocenter is a bioanalytical services company at the nexus of molecular biology, bioinformatics and high-throughput analysis, advancing research, clinical trials and diagnostic development. We support academic and industry partners with assay design, workflow optimization and validation, quality control, multiomics analysis, data analysis, reporting, tech transfer, trainings, and sample management. TATAA leads the nucleic acid analysis market with proprietary techniques engineered to support your research needs more efficiently and precisely.

Platinum

uniQure

uniQure is delivering on the promise of gene therapy, single treatments with potentially curative results. We have developed a modular technology platform to rapidly bring new disease-modifying therapies to patients treat patients with CNS, liver/metabolic and cardiovascular diseases.  We are advancing a focused pipeline of innovative gene therapies and have entered late-stage clinical development in our lead indication, hemophilia B, and have established preclinical proof-of-concept in Huntington’s disease.  

REGENXBIO Inc.

REGENXBIO Inc. is a leading clinical-stage biotechnology company seeking to improve lives through the
curative potential of gene therapy. Our gene therapy product candidates are designed to deliver
functional genes to address genetic defects in cells, enabling the production of therapeutic proteins or
antibodies that are intended to impact disease. Through a single administration, gene therapy could
potentially alter the course of disease significantly and deliver improved patient outcomes with long-
lasting effects.  We have developed a broad pipeline of gene therapy programs using our NAV ®
Technology Platform to address genetic diseases through two modalities: AAV-mediated antibody
delivery and monogenic gene replacement. We believe this platform forms a strong foundation for our
current programs and with our ongoing research and development, we expect to continue to expand
the platform.

Oxgene

OXGENE find solutions to seemingly impossible problems. We develop new technologies in mammalian cell engineering along the whole spectrum from discovery science to engineering at scale. Our unique combination of precision engineering and breakthrough science with advanced robotics and bioinformatics accelerates the rational design, manufacture and processing of complex biologics.
We work at the very edge of impossible to solve the problem of high titre virus manufacture for gene therapy treatments. We do this with high titre, high quality, suspension transient viral manufacturing systems, and with AAV and lentiviral packaging and producer cell lines. We address the challenge of speed and consistency in gene editing with our high throughput automated CRISPR platform, and we deliver the breakthrough needed to discover antibodies to membrane proteins through novel mammalian display techniques.

Orchard Therapeutics

At Orchard Therapeutics, our vision is to end the devastation caused by genetic and other severe diseases. We aim to do this by discovering, developing and commercializing new treatments that tap into the curative potential of hematopoietic stem cell (HSC) gene therapy. In this approach, a patient’s own blood stem cells are genetically modified outside of the body and then reinserted, with the goal of correcting the underlying cause of disease in a single treatment.

In 2018, the company acquired GSK’s rare disease gene therapy portfolio, which originated from a pioneering collaboration between GSK and the San Raffaele Telethon Institute for Gene Therapy in Milan, Italy. Today, Orchard is advancing a pipeline spanning pre-clinical, clinical and commercial stage HSC gene therapies designed to address serious diseases where the burden is immense for patients, families and society and current treatment options are limited or do not exist.

Orchard has its global headquarters in London and U.S. headquarters in Boston. 

Intellia

Intellia Therapeutics is a leading gene editing company, focused on the development of proprietary, potentially curative therapeutics using the CRISPR/Cas9 system. Intellia believes the CRISPR/Cas9 technology has the potential to transform medicine by permanently editing disease-associated genes in the human body with a single treatment course. Our combination of deep scientific expertise and clinical development experience, along with our leading intellectual property portfolio, puts us in a unique position to unlock broad therapeutic applications of the CRISPR/Cas9 technology and create a new class of therapeutic products. Intellia was named as one of the top 10 biotech start-ups by Nature Biotechnology. In September 2015, Intellia was named a “Fierce 15” biotech company by FierceBiotech

Pfizer

Pfizer Inc.: Breakthroughs that change patients’ lives®

At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as one of the world's premier innovative biopharmaceutical companies, we collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For more than 150 years, we have worked to make a difference for all who rely on us. We routinely post information that may be important to investors on our website at pfizer.com.

Spark Therapeutics

At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases. We have successfully applied our technology in the first gene therapy approved in both the U.S. and EU for a genetic disease, and currently have five programs in clinical trials. At Spark, we see the path to a world where no life is limited by genetic disease. Spark is a member of the Roche group. For more information, visit www.sparktx.com, and follow us on Twitter and LinkedIn.

Ultragenyx

Ultragenyx is a biopharmaceutical company committed to bringing to patients novel products for the treatment of serious rare and ultra-rare genetic diseases. The company has built a diverse portfolio of approved therapies and product candidates aimed at addressing diseases with high unmet medical need and clear biology for treatment, for which there are typically no approved therapies treating the underlying disease.
 
For more information on Ultragenyx, please visit the Company's website at ultragenyx.com.

AVROBIO

AVROBIO’s mission is to free people from a lifetime of genetic disease with a single dose of gene therapy. We aim to halt or reverse disease throughout the body by driving durable expression of functional protein, even in hard-to-reach tissues and organs including the brain, muscle and bone. Our clinical-stage programs include Fabry disease, Gaucher disease and cystinosis and we also are advancing a program in Pompe disease. AVROBIO is powered by the plato™ gene therapy platform, our foundation designed to scale gene therapy worldwide. We are headquartered in Cambridge, Mass., with an office in Toronto, Ontario. For additional information, visit our website, and follow us on Twitter and LinkedIn.

Forge Biologics

Forge Biologics is a hybrid gene therapy contract manufacturing and therapeutics development company.  Forge’s mission is to enable access to life changing gene therapies and help bring them from idea into reality.  Forge has a 175,000 ft2 facility in Columbus, Ohio, “The Hearth,” to serve as its headquarters.  The Hearth is the home of a custom-designed cGMP facility dedicated to AAV viral vector manufacturing and will host end-to-end manufacturing services to accelerate gene therapy programs from preclinical through clinical and commercial stage manufacturing.  By taking a patients-first approach, Forge aims to accelerate the timelines of these transformative medicines for those who need them the most.
 

WuXi Advanced Therapies

WuXi Advanced Therapies, a global Contract Testing Development and Manufacturing Organization (CTDMO), is the advanced therapies business unit of WuXi AppTec and offers integrated platforms to transform the discovery, development, testing, manufacturing, and commercialization of cell and gene therapies for customers worldwide. Our technologies, automation platforms and service solutions advance pre-clinical research and accelerate the timeline to GMP manufacture, while integrated GMP manufacturing and testing platforms reduce time to market, maintaining high titres, high levels of quality assurance and full regulatory compliance. Ultimately, our complete end-to-end solutions support pioneering companies to deliver breakthrough cell and gene therapies to the patients who need them.

Silver

Perkin Elmer

With about 14,000 employees worldwide, we pioneer scientific technologies for better detection, imaging, and informatics to help our customers make a profound impact on the world. We provide support with advanced services to ensure optimal operations.

Merck

We are Merck KGaA, Darmstadt, Germany the vibrant science and technology company. Science is at the heart of everything we do, it drives the discoveries we make and the technologies we create. Our products and services help you safely and efficiently develop and manufacture cell and gene therapies. Our BioReliance® Services support every stage of gene therapy development – from cGMP viral vector process development and manufacturing to a comprehensive set of biosafety tests in accordance with regulatory guidelines.
 
In addition, our SAFC® Biopharma Raw Material Solutions is a trusted manufacturer of specialty chemicals and biologics for life sciences and high technology commercial applications. The SAFC® portfolio of custom and ready-to-use critical raw material solutions are backed by an experienced and responsive team with deep technical, quality and regulatory expertise who can tailor solutions to precisely fit your process.

GenoSafe

GenoSafe provides analytical testing services for the evaluation of quality, safety and efficacy of Gene and Cell therapy candidates including:
· GLP biodistribution, shedding and immunogenicity studies;
· QC testing, such as viral titration, safety and potency/efficacy testing;
· GCP bioanalysis of patient samples, including immunogenicity, shedding and gene expression studies.
GenoSafe brings more than 15 years of experience in the development, qualification and validation of key analytical methods for product and sample testing.
 

FinVector

FinVector is a world leader in the research/development and cGMP manufacture of Viral-Based Gene Therapy products, with state-of-the-art facilities and a highly experienced scientific team working in the gene therapy market. We deliver a tailored service to meet and exceed our clients’ needs. With our scientific expertise and industry knowledge FVT help clients take viral-based products from pre-clinical through to commercial phase.

Aldevron

Aldevron serves the biotechnology industry with custom production of nucleic acids, proteins and antibodies. Featuring the largest and most modern GMP plasmid DNA manufacturing facility in the world, Aldevron provides thousands of clients with plasmids, RNA, gene editing enzymes and more for biological research projects from discovery to clinical trials and commercial applications. These products are critical raw materials and key components in commercially available drugs and medical devices, helping accelerate development of treatments for diseases such as cancer, infectious disease, pediatric disorders and rare diseases. Our collaborative approach and commitment to providing quality materials allow us to meet precise client requirements and provide innovative solutions to advance science. Aldevron headquarters is in Fargo, North Dakota USA, and additional facilities in Madison, Wisconsin and Freiburg, Germany.

VIVEbiotech

VIVEbiotech is a Contract Development and Manufacturing Organization -CDMO- developing and manufacturing lentiviral vectors under GMP standards with wide and robust experience in manufacturing vectors for rare/ultrarare diseases and for immune-cell therapy projects i.e. CAR-Ts, TCRs... 
 
VIVEbiotech is currently working on more than 35 projects according to both the FDA´s and the EMA´s regulations, and is manufacturing vectors for companies based in the US, Europe, Asia and Australia. 
 
VIVEbiotech has an R&D department as well as two process optimization departments for both upstream -USP- production and downstream -DSP- purification. The activities of these departments consist of improving the cost-effectiveness, scalability, regulatory or quality compliance of the production process, and the intrinsic biological characteristics of the vectors themselves.
 
VIVEbiotech very recently expanded facilities and has now seven cleanrooms fully and specifically set up for lentiviral-vector manufacturing. This has allowed significantly increasing our production capacity. 
 
In these facilities VIVEbiotech will be capable of manufacturing from early-stage to clinical- and commercial-scale batches.
 

Paul-Ehrlich-Institut

The Paul-Ehrlich-Institut (PEI), Federal Institute for Vaccines and Biomedicines, is a world-renowned scientific institute devoted to improving public health by ensuring the safety and efficacy of vaccines and biomedicines both in Germany and throughout the world. PEI carries out its mission through scientific research and medicinal product regulation. Internationally competitive research is carried out in the fields of virology, microbiology, allergology, immunology, hematology and cell and gene therapy.

KCT

KCT is newly formed research center in Kuopio, Finland. We provide high quality basic and translational research. Professional team and laboratories with cutting edge devices are providing scientific know-how and modern technologies to develop advanced therapies. We undertake science in collaboration with academic groups all over the world. Link to FinVector's GMP manufacturing, quality and regulatory teams ensures product path from research to patients.
 

Sarepta Therapeutics

Sarepta Therapeutics is on an urgent mission: engineer precision genetic medicine for rare diseases that devastate lives and cut futures short. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development. Our vast pipeline is driven by our multi-platform Precision Genetic Medicine Engine in gene therapy, RNA and gene editing.

Asphalion

Asphalion is an international Scientific and Regulatory Affairs consultancy, with offices in Barcelona, Madrid and Munich. We collaborate with Pharma and Biotech companies facilitating Drug Development and Regulatory Affairs projects for Drugs, Biologics, Biosimilars, ATMPs and Medical Devices. Our involvement ranges from early development, through to registration and post-commercialization phases. Since the company was founded in 2000, we have consistently grown and now have a team of over 80 employees with backgrounds in all areas of life sciences. Our consultants are experts in their fields and are in direct contact with European agencies for the implementation of new regulatory standards. We provide global services and work for hundreds of clients from around the world. Through collaborations with partners in all other continents, we can accelerate your worldwide scientific and regulatory activities by using local expertise.
Services:
• Regulatory and Scientific Strategy during Development
• Medical and Scientific Writing
• Global Submissions
• eSubmission and RIM
• Life-Cycle Outsourcing
• Pharmacovigilance
• Promoting the marketing registration of Medical Devices: Classification strategy, CE Marking and compilation of technical file. 

Clean Cells

BIOSAFETY TESTING
A full range of regulatory tests in compliance with GLP and cGMP, with more than 200 qPCR tests available. Capability to develop and validate innovative, sensitive, specific and robust tests in accordance with ICH Q2 R1.
 
GMP PRODUCTION and STORAGE
Production of Eucaryotic and Procaryotic cell banks, Viral banks and Storage in liquid nitrogen or -80°C.
 
ASSAY DEVELOPMENT
Production of cell models which express molecules of interest.
Transfection, cloning, selection, amplification.
Analysis in vitro of the cell responses: measurement of viability, proliferation, phenotype, specific functions (ex. ADCC, apoptosis, CDC), interferon activity.
Development and validation of qPCR tests: detection quantification of pathogens or contaminants, residual DNA, determination of sites of insertion of a transgene, gene copy number.
Development and validation of virus titration method. 
Detection and validation of recombinant competent replication tests (rcAAV,RCL) for gene therapy.
 
ADVANCED MEDECINE THERAPY MANUFACTURING FOR PHASE I/II
GMP manufacturing platform for bacteriophages and cell therapy products for phase I / II clinical trials.
 

Biocair

Biocair is a global specialist courier with over 30 years of dedicated experience in the pharmaceutical, biotechnology and life science sectors. Specifically, we provide dedicated, specialised logistics services – both the systems and the people – for the scientific sector and our services are the most comprehensive of its kind available on the market.

The company has built up a unique, client-centric approach by employing scientists in front- line logistics positions and assembling a team of best-in-class industry experts in quality, cold chain and regulatory compliance amongst others. Biocair focuses on providing the most comprehensive time-sensitive and temperature-controlled logistics services available whilst delivering flexible, tailored, cost effective solutions to all clients.

The Biocair network spans more than 850 locations in over 160 countries across Europe, Africa, Asia and the Americas.

Univercells Technologies

Univercells Technologies is a global provider of innovative biomanufacturing technologies to achieve cost-effective viral production from R&D to commercial scales. The company offers a comprehensive technology portfolio leveraging the strengths of process intensification and chaining as a direct answer to the growing demand for viral vectors and viral vaccines. Univercells Technologies is committed to helping customers increase performance with minimized footprint and costs today, while anticipating the needs of tomorrow.

Building upon years of expertise and capitalizing on technology vetted by world leaders, Univercells Technologies was incorporated in Belgium in 2020 with the support of the Univercells group.
 

NHSBT

NHS Blood and Transplant is a national organisation within the NHS dedicated to saving and improving lives.

Our Cellular and Molecular Therapies function offers broad experience and expertise in the provision and manufacture of cell and gene therapies through our national network of GMP grade and MHRA licensed facilities.
NHSBT partner with academic, commercial and NHS organisations supporting novel cell and gene therapy programmes from concept through to clinical trial, operating a ‘not for profit’ model. 

We welcome expressions of interest for partnerships with organisations striving to develop the future of medicine in the advanced therapies space.

Polyplus-transfection

Polyplus-transfection applies its 20 years expertise to the development of novel transfection solutions. Polyplus-transfection is the leading supplier of a key critical component for viral vectors manufacturing for Gene & Cell Therapy. We are proud to provide qualified and GMP-grade transfection reagents suitable from R&D to clinical trial and commercial scale, accompanied by a strong scientific and regulatory support. In addition, we provide a range of effective transfection reagents to deliver most nucleic acids, including DNA and siRNA in vitro and in vivo.
 

Takara Bio Europe

Takara Bio Europe is a subsidiary of Takara Bio Inc., who offers a wide range of life science reagents under the Takara™, Clontech®, and Cellartis® brands.
 
Key products include SMART cDNA synthesis kits for a variety of samples and applications, including NGS, high-performance qPCR and PCR, Cellartis stem cells solutions, the innovative In-Fusion® cloning system, Guide-it gene editing tools.
 

Passage Bio

Passage Bio is a clinical-stage genetic medicines company on a mission to provide life-transforming therapies for patients with CNS diseases with limited or no approved treatment options. Our portfolio spans pediatric and adult CNS indications, and we are currently advancing three clinical programs in GM1 gangliosidosis, Krabbe disease and frontotemporal dementia with several additional programs in preclinical development. Based in Philadelphia, PA, our company has established a strategic collaboration and licensing agreement with the renowned University of Pennsylvania’s Gene Therapy Program to conduct our discovery and IND-enabling preclinical work. Through this collaboration, we have enhanced access to a broad portfolio of gene therapy candidates and future gene therapy innovations that we then pair with our deep clinical, regulatory, manufacturing and commercial expertise to rapidly advance our robust pipeline of optimized gene therapies. As we work with speed and tenacity, we are always mindful of patients who may be able to benefit from our therapies.
 

Cellex

MANY TASKS. ONE NAME: CELLEX CELL PROFESSIONALS – WE CARE FOR LIFE
Cellex is offering a broad spectrum of services for clinical as well as for research institutions in the field of cellular therapies.
Cellex started its operation with a Cellex collection center in 2001 offering stem cell collections from unrelated donors for leukaemia patients. Today Cellex is the largest and most experienced center worldwide.
Today in our state-of-the-art GMP facilities different cell therapy products are manufactured using various techniques (separation, genetic modification, expansion); processes are adapted to customers’ needs.
Our donor pool “CellCommunity” allows us to support R&D as well as clinical trials and supply research institutions worldwide with cell material.
Centralized management of all different runs with the help of secure and efficient IT solutions, developed by Cellex as well as transports worldwide support are an essential part.
Beside Cellex develops individual cell therapies and is conducting early clinical studies on new therapeutic approaches.
 

Eurogentec

The Bio-Manufacturing business unit is a cGMP accredited Contract Manufacturing Organization (CMO) that produces recombinant proteins and plasmids from microbial fermentation and IVT-RNA for clinical and commercial phases.
Eurogentec provides a wide range of services: process transfer and development, cGMP manufacturing, Quality Control, bulk release.
 
In 2020, Eurogentec launched a 1500L commercial line.
 
Plasmid: Cost-effective manufacturing of GMP starting material or injectable API pDNA.
rProtein: Significant experience in the protein production from Yeast (P.pastoris, S.cerevisiae, etc) and bacteria (E.coli).
IVT-RNA: Eurogentec is a pioneer in GMP in vitro transcript RNA. Our new facility can adapt to many different processes including availability of various modifications (co- or post-transcription).
 
With over 20 years of experience as CMO, you benefit from our broad manufacturing experience. Our philosophy is to establish a close partnership with our clients, adapt to their project needs and to provide them with cost and time efficient production processed.
 

Myriade

Myriade develops the VIDEODROP, an innovative nanoscale imaging technology. 

Based on the principles of interferometry, the Videodrop makes it possible to measure the size and concentration of biological nanoparticles like lentivirus, adenovirus or retrovirus 

  • in real time (40s) 
  • in a single drop (5µL) 
  • between 80nm & 500 nm 
  • in a concentration range of 10E8 to 10E10 part/ml 
  • without labelling & no purification 
  • on viscous & complex samples 
Videodrop measures the physical titer of viral vector solutions, so it allows to: 
  • Continuously monitor bioproduction processes thanks to its rapidity of measurement (40s) 
  • Work on real samples at any stage of the bioproduction in a non-denaturant way 
  • Control the yield of vector production after harvesting, Purification, or Concentration steps 
  • Quickly identify lot-to-lot variations 

Providing linear results compared to p24 ELISA, VIDEODROP is suitable for "at-line" characterization of lentiviral vectors and in-process controls. 

 

ArcticZymes Technologies

ArcticZymes Technologies ASA is born from the unique conditions in the Arctic and our labs in Tromsø (Norway), we have been developing and producing cold-adapted enzymes for more than 30 years.
 
Our high-quality enzymes are an integral part of molecular research and diagnostics, either as stand-alone enzymes or as components of kits. In therapeutics such as gene therapy and vaccine production our enzymes aide the optimization of manufacturing processes.
 
All our products are manufactured to ISO 13485 standards and meet all REACH requirements. The unique features of our premium enzymes are accompanied by our dedication to quality, and a no-compromises approach to collaborate with our clients and partners.
 
ArcticZymes Technologies is trusted by leading molecular research kit manufacturers, diagnostic assay developers, contract manufacturers, and therapeutic companies around the world.

Progen

PROGEN - Making life science better. Together.

PROGEN was founded in 1983 by four scientists from Heidelberg, Germany, who joined forces to manufacture and supply high quality antibodies for biomedical research. We help scientists worldwide drive biopharmaceutical and diagnostic progress to provide high-quality and reliable treatments for patients. Our mission is to make new therapies safe and affordable and to improve existing research processes.
The PROGEN team consists of bioscientists and adeno-associated virus (AAV) experts who collaborate with specialists around the world. Our products are essentials for research in science and industry.
We are more than just a manufacturer of antibodies, AAV gene therapy tools, density gradient media, and phage display technologies: We strive to understand the needs of scientists to develop solutions to jointly address challenges in academic research, biotechnology and pharma.

VGXI Inc

VGXI, Inc. is a leading contract manufacturer of DNA-based pharmaceuticals with 20 years of experience providing high quality cGMP products to clinical trials worldwide. Uses include DNA vaccines, immunotherapies, and cell and gene therapy applications. The company's continuous, low-shear AIRMIX® lysis technology and optimized purification process provide highly supercoiled plasmid with exceptional purity across all manufacturing scales. Production services include high quality plasmid for preclinical research, Highly Documented (HD) plasmid as a critical raw material for GMP viral vector production or pharm/tox studies, and cGMP plasmid DNA for clinical through commercial supply. Pre-Clinical through GMP RNA manufacturing services are also available.
 

Lonza AG

At Lonza, we provide contract development and manufacturing services that enable pharma and biotech companies to bring medicines to patients in need. From the building blocks of life to the final drug product, our solutions are created to simplify your outsourcing experience and provide a reliable outcome when you expect it. Our extensive track record includes commercialization of pioneering therapies and manufacturing of a wide variety of biological and chemical drugs. We continuously invest to solve not just the current, but also the future challenges.

Together, let’s bring your next medicine to life.

Cergentis

Cergentis is a privately held genomics company and has developed and patented the Targeted Locus Amplification (TLA) technology. TLA is a widely published Next Generation Sequencing (NGS) technology that offers unique advantages in the implementation of advanced genetic engineering.
We develop and sell services and in-house solutions for targeted and complete sequencing of (trans)genes and gene editing events and provides services for the support in R&D in these fields. Founded in 2012, Cergentis has established itself as a trusted partner and leader in robust and rapid genetic characterization of genetically engineered cell lines, cell and gene therapy products and transgenic (animal) models for the global biopharmaceutical industry as well as leading research institutes worldwide. It is our mission to improve the quality of genetic research: supporting biopharmaceutical R&D will accelerate the development of new treatments with better outcomes for patients all over the world.
 

VectorBuilder

As a global pioneer in custom DNA vectors and recombinant viruses, VectorBuilder’s revolutionary online-to-offline (O2O) platform provides a powerful one-stop solution to all the vector and virus needs in the life sciences. VectorBuilder has a wide spectrum of offerings, including:

- Vector design
- Custom cloning
- Virus production (AAV, adenovirus, lentivirus, etc.)
- AAV capsid evolution and biodistribution services
- mRNA production
- Library construction
- Recombinant Protein Production
- Stable cell line generation
 
Additionally, our state-of-the-art GMP facilities provide GMP-grade plasmid and virus manufacturing for a wide range of clinical applications. 
 
 

PeproTech

PeproTech, part of Thermo Fisher Scientific, specialises in the development and manufacture of high-quality cytokine products for the life-science and cell therapy market. 

With more than 30 years’ manufacturing experience, PeproTech’s range of RUO, Animal-Free and GMP cytokines offers the performance and reliability that you need.

With over 2,000 products, PeproTech has developed and refined innovative protocols to ensure quality, reliability and consistency.

Our mission is to provide the highest quality products and premium support that address the needs and demands of today's scientists and researchers.

We pride ourselves on being a trusted partner within the scientific community.

Please contact PeproTech to request a quote or discuss your research requirements:

Tel: 020 7610 3062 or Email: info@peprotech.co.uk

Aseptic Technologies

ASEPTIC TECHNOLOGIES develops, manufactures and markets innovative aseptic solution for the BioPharmaceutical industry.
 
Its equipment and devices are designed to de-risk aseptic fill and finish, the best-known being the AT-Closed Vial® technology.
 
The AT-Closed Vial® is based on the unbreakable ready-to-use vial, supplied with stopper in place and remaining closed throughout the filling process, minimizing the contamination risks.

Various equipment offer an easy scale-up from manual to fully automated operation.
 
The benefits of the technology are: better sterility assurance, fast operations, scalability, increased safety during whole supply chain, strong operating cost reduction.
 
The AT-Closed Vial® technology is widely used in the Cell and Gene Therapies as it offers uncompromised container closure integrity even during storage at -80°C and cryogenic temperatures.
 

PackGene Biotech

PackGene is a leading CRO and CDMO company providing AAV-based gene therapy solutions to institutions and biotech companies. Ever since it was founded in Massachusetts in 2014, PackGene has been focused on providing expertise, reliability, scalability, and efficiency in AAV packaging services and AAV manufacturing.
PackGene has a 90,000+ ft 2  custom-designed cGMP facility, dedicated to plasmid DNA and AAV viral vector manufacturing, from GLP grade to GMP grade. We are experts in process development, scale-up as well as analytical testing. This is underpinned by a well-established safety framework, a track record of quality and compliance, a robust supply chain and access to skilled scientists.
Our goal is to collaborate with biotech companies and institutions to accelerate gene therapy programs from early discovery, preclinical stage through clinical, and on to commercial manufacturing.

Barkey GmbH & Co.

Barkey is a German family business for medical technology in the field of warming devices. Founded in 1980 by Volker Barkey, Thomas and Christian Barkey together with Armin Nowack and the entire staff have led the company to worldwide awareness in the hospital and blood bank sector as well as in cell & gene therapy research.

Barkey has two main goals: Preventing hypothermia and advancing Cell & Gene research to develop new cancer therapies. For this purpose, Barkey produces various solutions for warming or thawing blood, blood products and cellular materials, infusion solutions, etc. The safety of the samples, the user and, of course, the patient is of priority. Barkey relies exclusively on dry heating systems since the use of open water baths offers a high risk of contamination. This must be avoided both, during the preparation of patient treatment and during the research and production of new therapeutic procedures.
 

ChemoMetec A/S

ChemoMetec is a leading manufacturer of cell counting and analysis equipment. We specialize in developing and producing high-precision instrumentation that delivers consistent data for thousands of customers across segments including biotech, pharma, and academia.
 
Our NucleoCounter® instruments dominate the cell therapy space. They are the most robust and consistent cell counters on the market. What’s more, they are standardized for easy deployment across departments, and they are 21 CFR Part 11-ready, enabling you to fully integrate single or multiple instruments into your existing IT networks.
 
Designed, manufactured, and tested in Denmark, we build our instruments and consumables with quality materials and dedicated expert workmanship.

 

Fluidigm

Fluidigm Corp creates, manufactures, and markets technologies and life-science tools focused on the exploration and analysis of single cells, as well as the industrial application of genomics, based upon microfluidics and mass cytometry technologies.

Mission Bio

Mission Bio is a life sciences company that enables comprehensive characterization of your cell and gene therapy candidates for safer and more effective therapeutics. The company’s Tapestri Platform empowers developers to accurately assess multiple genotypic attributes in a single assay, including on- and off-target gene editing, zygosity, chromosomal aberrations, transduction efficiency, and vector copy number— in 1000s of individual cells. The platform’s robust multi-omics capability enables DNA and cell-surface proteins to be co-measured in the same cells, providing information on genotype and cell type/ state. Mission Bio partners with biopharma to provide full-service Pharma Assay Development — including experimental design, lab work, and bioinformatic analysis — so you can leverage single-cell analysis in your preclinical, clinical, and commercial efforts.
 

Unchained Labs

Here’s the deal. We’re all about helping biologics and gene therapy researchers break free from tools that just don’t cut it. Unleashing problem-tackling products that make a huge difference in the real science they do every day. That’s our mantra, our promise and we own it.
 

Proteintech Europe

Proteintech manufactures antibodies, immunoassays, HumanKine recombinant proteins and ChromoTek Nanobody-based reagents.
 
Proteintech’s comprehensive library of original validation data, product-specific protocols, and over 130,000 product citations enables you to publish faster with reproducible results.   

  • Antibodies against over 13,000 human targets
  • Immunoassay kits
  • RUO and GMP HumanKine cytokines and growth factors
  • ChromoTek Nanobody-based reagents
  • Supporting tools and reagents

 Browse the full product range at ptglab.com or contact europe@ptglab.com to learn more about our products and promotional offers.

Samplix

Samplix supports the life sciences and medical research communities with proprietary microfluidics-based solutions designed to deliver the highest-resolution insights into cells and genomes. Our technology encapsulates single mammalian, bacterial or yeast cells, DNA, and other biological material together with assay chemistry. This supports a range of downstream analyses: functional analyses of single mammalian cells, assessments of single-cell enzyme activity, characterization of edits in engineered genes, and even cell incubation. As a leading developer of microfluidics solutions, Samplix stands ready to help researchers reach their goals in areas as diverse as gene and cell therapy, synthetic biology, and molecular engineering.
 

SIRION Biotech

SIRION Biotech GmbH is a leading commercial supplier of viral vector technologies (AAV, LV, AV). Our viral vector know-how enables engineering for a new generation of optimized vectors.
 
We guide our customer through the entire Cell & Gene Therapy value chain – from capsid evolution and clinical vector design to reduce vector dose and improve therapeutic success, to supporting them with our process and development experience and manufacture of high-quality clinically compliant viral vectors for late preclinical applications.
 
We also offer LentiBOOST®, a highly effective lentiviral transduction enhancer for therapeutic cell types like CAR-T cells and CD34+ hematopoietic stem cells. LentiBOOST is currently included in more than 20 Phase III and I/II clinical trials and is available in research and GMP grades.
 
The company is located near Munich with offices in Paris and Boston. Commercial arrangements range from fee-for-service and IP-generating collaborations to milestone & licensing arrangements.
 

Grifols Bio Supplies

Grifols is a global healthcare company that since 1909 has enhanced the health and well-being of people around the world. Our four divisions – Bioscience, Diagnostic, Hospital and Bio Supplies – develop, produce and market innovative solutions and services in more than 100 countries.

The Bio Supplies Division supplies high-quality biological materials for biotechnology research, clinical trials, and for manufacturing pharmaceutical and diagnostic products.

Grifols, with more than 24,000 employees in 30 countries and regions, is committed to a sustainable business model that sets the standard for continuous innovation, quality, safety and ethical leadership in the industry.

Andelyn Biosciences

Andelyn Biosciences is pioneering solutions that turn hope into reality as a cell and gene therapy CDMO. Capabilities span viral vector process and analytical development, small to large scale adherent and suspension based GMP manufacturing up to 2000L. Having 20+ years of experience with viral vector manufacturing, Andelyn offers access to globally recognized thought leaders with troubleshooting/characterization expertise and GMP material produced for 75+ worldwide clinical trials. In addition to producing 400+ cGMP clinical batches, Andelyn provides research and tox grade plasmids with an additional offering of GMP plasmid manufacturing, full quality system/regulatory support and supply chain vertical integration. Its state-of-the-art 185,000 sq ft commercial manufacturing facility will expand capacity across 16+ production suites for customization of new programs and tech transferred programs as of 2H 2022, offering clinical through commercial-scale capabilities that will help accelerate innovative therapies to bring more treatments to more patients.
 

JPT Peptide Technologies

JPT provides products and services for all the development phases of next generation immunotherapeutics. With sound knowledge in immunology and peptide chemistry, we offer peptides and peptide pools (PepMix™) for antigen-specific stimulation of cells, humoral and cellular epitope mapping, viral transduction, and development of immunotherapies. 

Thanks to an enhanced production protocol, our peptides are the product of choice for the development of cell therapies such as adoptive cell transfer or dendritic cell pulsing independent if you are aiming for an individualized neo-epitope approach or working with shared and common antigens. 

With our novel transduction enhancer Protransduzin™ the generation of CAR-Ts or TCR-Ts can be streamlined by enhancement of viral transduction in a simple one-step protocol.  Humoral immune response is addressed with our PepStar™, high-content microarrays for seromarker discovery and multiwell microarrays for profiling up to 20 samples.

Symbiosis

Symbiosis Pharmaceutical Services is a contract development and manufacturing organisation (CDMO) specialising in the GMP manufacture and sterile fill/finish of vials for clinical trials and commercial supply. Regulatory compliance, technical capability and operational flexibility are at its core.
 
Manufacturing from a purpose-built FDA inspected and MHRA-licensed facility, the CDMO can handle products that require aseptic liquid filling and lyophilisation for a range of complex biologics, viral vectors for use in gene therapies and small molecule drugs.
 
Offering fast access to manufacturing slots and accelerated release of drug product, Symbiosis is primed to meet demand for small-scale, fast-turnaround drug product sterile manufacturing.
 

Kriya

Kriya is a fully integrated gene therapy company on a mission to revolutionize how gene therapies are designed, developed, and manufactured – with a goal of improving speed to market and reducing cost. The company leverages its proprietary computational engine, in-house manufacturing infrastructure, and integrated design platform to engineer products with the potential to transform the treatment of a broad range of diseases. Kriya’s team includes scientific pioneers with decades of experience in product development, complex manufacturing, and computational engineering.

The company has established an ecosystem for delivering best-in-class technologies and medicines, with core business units in technology, manufacturing, R&D, and therapeutics. Kriya’s product pipeline addresses diseases of high unmet need with therapeutic area divisions in ophthalmology, oncology, rare disease, and chronic disease, each led by industry veterans with a track record of advancing products from concept through commercialization. Built upon this foundation, Kriya achieves the scale needed to drive transformational improvements in the engineering, production, and translation of gene therapies. 

FUJIFILM Irvine Scientific

FUJIFILM Irvine Scientific is a worldwide leader in the innovation and manufacture of cell culture media, reagents, and medical devices for researchers and clinicians. We provide unrivaled service and quality to scientists working in cell therapy and regenerative medicine, assisted reproductive technology and cytogenetics, and bioproduction for commercial manufacturing of biotherapeutics and vaccines.

Our commitment to supporting the biopharmaceutical industry in the successful development and commercialization of human therapeutics and vaccines is evident in the alignment of our technology, support, and supply capabilities to meet and exceed the distinctive requirements of the market. While remaining a uniquely flexible and focused media company for over 50 years, FUJIFILM Irvine Scientific has steadily advanced as a strategic global supplier in support of our customers from early development to commercialization.
 

Evotec

Evotec is a life science company with a unique business model focused on providing access to highly effective new therapeutics. The Company leverages its multimodality platform with a unique set of innovative technologies for both proprietary and partnered projects.